Introduction
Background
Proliferation
Cell Cycle
Mutations
Euploidy
Polyploidy
Aneuploidy
Duesbergs Hypothesis
Pathology
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You are here Background | Cell Cycle

   
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The cell cycle

 
Regular sequence of events during cell-life from its origin from a parent-cell to its own division into two daughter cells

Comprises M-, G1-, S- and G2-phases

 
 

M = Mitosis
G1 = Gap1
S = DNA- synthesis
G2 = Gap2
Interphase = G1-, S- and G2-phases

 
G0/1-phase cells are resting or differentiating to gain specific functions
and do not divide
 
Abnormal DNA-histogram of bile duct adenocarcinoma cells (red), illustrating three cell cycle phases: G0/1 93%, S-phase 2% and G2/M-phase 5%. Abnormal DNA-stemline at 3,5c. Normal diploid epithelial cells at 2c (green)
 
 
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Numerical chromosomal
aberrations (aneuploidy)
may occur during mitosis