Introduction
Background
Proliferation
Cell Cycle
Mutations
Euploidy
Polyploidy
Aneuploidy
Duesbergs Hypothesis
Pathology
Indications
Methods
Diagnostic Materials
Measurements
Multimodal Cell Analysis
Quality Control
Diagnostic Interpretation
Diagnostic Applications
Case Reports
Responsabilities
References
Terminology
Abbreviations
Contact
Sitemap
1
 
You are here Background | Mutations
   
 

Mutations

spacer
Mutations are changes in coding DNA (~genetic information) of a cell affecting derived RNA and proteins
 

Genemutations affect single or fewbase-pairs, e. g. by point mutation, insertion, deletion or inversion

 
Chromosomal mutations affect number or structure of chromosomes,
e. g. by gain, loss or translocation
Whereas the effect of gene-mutation cannot be indentified by cytometry, that of chromosomal mutation can if the amount of cellular DNA-changes is greater than the error of measurements (currently about 2 %).
 
 
 
 
 
 
 
 
 
 
 
 
 
-

Mutations do not change nuclear DNA-content