| Diagnostic DNA-ICM is used
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| to assist in the early microscopical diagnosis and grading of various types of tumors, measuring the DNA-contents of their cells |
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| Diagnostic DNA-ICM works by |
| determination of nuclear DNA-contents, deposited on glass slides and specifically stained on images by measurements of their integrated optical densities (IODs). |
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| Diagnostic DNA-ICM requires |
| a microscope equiped with a video- or CCD-camera, a personal computer equiped with a specific application software for densitometric image analysis and diagnostic data-interpretation and cells from a suspicious lesion of the human body on glass slides, specifically stained for DNA |
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| Diagnostic DNA-ICM is based on |
chromosomal aneuploidy
 a specific marker for tumor cells |
| DNA-aneuploidy |
| the cytometric equivalent of chromosomal aneuploidy |
| a sensitive and specific marker for tumor cells |
| that is derived from DNA-histograms |
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