Introduction
Background
Pathology
Indications
Methods
Type of Materials
Preparation & Fixation
Cell Separation
Feulgen Staining
Protocolls
Chemicals
Instruments
Storage of Slides
Diagnostic Materials
Measurements
Multimodal Cell Analysis
Quality Control
Diagnostic Interpretation
Diagnostic Applications
Case Reports
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References
Terminology
Abbreviations
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You are here Methods | Type of Materials
 
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Surgical Specimens
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quarter All types of formalin-fixed and paraffin-embedded tissues deriving from autopsies, operations
or biopsies after enzymatic cell separation of the diagnostically relevant regions (see chapter
cell separation)
quarter DNA-measurements on sections are not precise enough for diagnostic purposes and should
not be performed
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Paraffin-embedded tissue and corresponding H.E.-stained section with marked region Scalpell
and punch-biopsy-neddles, paraffinblocks and sections of interest

 
Punch biopsies
 
quarter All types of formalin-fixed cutting needle- or forceps biopsies after enzymatic cell separation
quarter DNA-measurements on sections are not precise enough and should not be performed
 
instruments
Scalpell and punch-biopsy-neddles, paraffinblocks and sections
 
Fine-needle-aspiration-biopsies
 
quarter All smears from fine-needle-aspiration biopsies irrespective of primary fixation
quarter Smears from all types of fine needle aspiration biopsy irrespective
of previews fixation and staining
 
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Fine needle aspiration-biopsy of a thyroid nodule
 
Smears
 
quarter All types of smears from exfoliated cells (brushings, scrapings, sediments)
irrespective of previous fixation
 
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Brush-biopsy from the cornea, Brush-biopsy from the oral mucosa
 
 
 
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Paraffin embedded
tissue suitable
after enzymatic
cell separation

 


 

 

 

 





 
 
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Paraffin embedded
tissue is suitable
after enzymatic
cell separation

 


 

 

 

 
 
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Cytologic samples
are best suited
for DNA-ICM