Introduction
Background
Pathology
Indications
Methods
Diagnostic Materials
Measurements
Multimodal Cell Analysis
Principles
Mesiotheliomas
Thyroid Cancer
Oral Cancer
Advantages
Quality Control
Diagnostic Interpretation
Diagnostic Applications
Case Reports
Responsabilities
References
Terminology
Abbreviations
Contact
Sitemap
1 2 3
 
You are here Multimodal Cell Analysis | Principles
 
spacer

Multimodal Cell Analysis (MMCA) for Diagnosis of Malignant Mesotheliomas

 

quarter Application of different modes of cell-analysis, e.g.

1. Cytomorphology

2. AgNOR-analysis
3. DNA-image-cytometry
4. Immuncytochemistry
5. Fluorecence in-situ-hybridisation
on different slides of the same specimen = parallel MMCA on same slide of a specimen
= sequential MMCA
   
Parallel MMCA on mesiothelioma cell
(on different cells)
1. Cytomorphology (MGG-stain)
2. DNA-image-cytometry (Feulgen-stain)
3. AgNOR-analysis (silvernitrate-stain)
4. Immunocytochemistry (Calretinin)
5. Chromosomal FISH (p21 deletion)
 
 
 
-

Combination of different modes
of analysis on same
material or cells